OLYMPIC COOL-CAP® SYSTEM CHANGING THE STANDARD OF CARE IN THE NICU FOR NEONATES WITH HIE The only FDA approved device for the treatment of hypoxic-ischemic encephalopathy (HIE) in term infants, the Olympic Cool-Cap System is a unique and complete system utilizing a special cooling cap to provide selective brain cooling while maintaining core temperature at safe levels through the use of a radiant warmer. Administered to newborns within the first six hours of life, treatment with the Olympic Cool-Cap System can prevent or significantly reduce the severity of neurologic injury associated with HIE. Neonatologists at Arkansas Children's Hospital treat first infant with the Olympic Cool-Cap System FDA Patient Safety News Featuring the Olympic Cool-Cap System

CLINICAL BENEFITS

• Provides neuroprotection while minimizing the side-effects due to hypothermia
• Allows neonatal brain cooling while maintaining patient's core temperature at safe levels
• Results in meaningful improvements in neurodevelopmental outcome and survival rates at 18 months of age
• Improved outcome for babies with early intervention

BETTER TREATMENT THROUGH BETTER DIAGNOSIS

• The Olympic CFM 6000 cerebral function monitor helps assess the extent of HIE to determine if cooling is indicated
• When used in conjunction with the Cool-Cap System, the CFM 6000 monitor provides greater confidence in managing & treating babies in the first few hours of life

PROVEN SAFE & EFFECTIVE

In a randomized-controlled, multi-center, international clinical trial, the Olympic Cool-Cap system was shown to reduce or prevent neurological damage associated with HIE in some infants¹

¹References available upon request.

SYSTEM COMPONENTS

Control Unit

• Easy-to-use touch screen design
• Built-in protocols with wizard instructions help guide the user through treatment

• Solid-state water cooler with precise temperature control
• Very reliable and quiet
• Simple, fast, safe and clean filling & draining
• Temperature displays: cooling cap, neonatal rectal, scalp, skin & optional sensors

Cooling Cap Three-piece set in three sizes (small, medium, large) Insulated outer cap Helps maintain cooling temperature by reflecting external heat from radiant warmer Water-cap retainer Holds water-cap securely in place Water-cap Soft water-circulating channels provide efficient, controlled and uniform cooling contact without pressure points

TREATING NEONATES
Simple Operation with Sophisticated Results

• Wizards & Prompts - simply follow the built-in protocol to administer treatment
• Initiate Treatment Quickly - enter only weight & gestational age to start cooling
• Lower Neonate's Temperature - ensures safety with continuous temperature displays & trend data, while alarms assure a safe cooling technique
• During cooling, enter real-time clinical notes directly on screen for review
• Maintains brain cooling for 72 hours while maintaining core temperature of 34-35° C
• Rewarm the infant - monitored & controlled rewarming for 4 hours
• Simply drain water into bag for disposal - no internal cleaning of unit required

Cool-Cap® is a registered trademark of Tiara Medical Systems, Inc.